The use of Li-ion batteries (LIBs) is increasing worldwide. Even though  this has numerous benefits, LIBs also pose specific risks to workers’  safety and health, especially in terms of chemical safety.  The objective of this study was to examine the occupational safety of  the LIB value chain and to determine the good practices and aspects that  need to be taken into account in the management of the safety risks  related to LIBs. In addition, Life Cycle Assessment (LCA) was used as  the tool for evaluating the environmental impacts throughout the value  chain of the LIB selected for the case study. The assessment also  considered the gaseous emissions occurring over the lifetime of the  battery. The study methods consisted of literature reviews, document  analysis and semi-structured interviews. The chemical hazards at all the  stages of the value chain were classified and accidents occurring  during the use and end-of-life phases were also considered. The  classification was based on the EU Classification, Labelling and  Packaging (CLP) system (EU regulation No 1272/2008), and on the  identification of gas emissions in accidents found in the LIB  literature. We used these classifications and LCA results to design  guidelines. The study looked at nine companies representing different  phases of the LIB value chain, located in Finland and Spain, and their  relevant stakeholders and authorities.  The most critical risks in the value chain and risk management measures  were elicited in the interviews. The safety management evaluation of the  value chain was modelled on the information gathered from the  interviews and from existing research. This safety management evaluation  model provides criteria for a three-level approach to safety. The  increasing amount of forklift trucks using LIBs as well as the variety  of the age and size of LIBs in use are expected to increase the risks  for safety. Companies manufacturing, using and handling LIBs place a  great effort into preparedness and competence. More co-operation with  fire and rescue authorities is highly recommended. As LIBs are becoming  more common, it is increasingly important in risk assessment to pay  attention to how they are transported, stored, handled and recharged.