Industrial installations handling hazardous chemical substances can generate cascading effects across interconnected infrastructures, potentially amplifying accident consequences well beyond the initial site. Traditional safety analyses often consider installations in isolation and do not fully address interdependencies between critical infrastructures such as energy, transport and communication systems. This limits the ability to anticipate and manage cascading scenarios that can escalate industrial accidents into wider societal crises. The H(CS)2I project addresses these challenges by analysing cascading effects and interdependencies involving hazardous chemical installations, with the aim of improving risk assessment and emergency planning.